Database of genetically modified malaria parasites

Search for genetically modified parasite lines

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The site Pberghei.eu hosts the RMgm-database which contains information on genetically modified malaria parasites generated by many laboratories around the world (over 5000 mutants; August 2021). It contains data of three rodent malaria parasites: Plasmodium berghei, P. yoelii and P. chabaudi. The database provides the research community with access to information on the generation and phenotypes of mutant/mutated malaria parasites (e.g. gene deletion, gene-tagging, gene mutation, transgene expression). The database also provides information on (un)published mutants without a clear phenotype and negative attempts to delete genes. RMgmDB has been described in several papers. • Trends in Parasitology • Methods in Molecular Biology • Methods in Malaria Research

The information in RMgmDB is shared with and linked to the following databases:  the database of ‘EuPathDB Bioinformatics Resource Center for Biodefense and Emerging/Re-emerging Infectious Diseases’ (www.PlasmoDB.org), the database/website of the Sanger Plasmodium Genetic Modification Project (PlasmoGEM) and the PhenoPlasm database (PhenoPlasm).

The RMgm-datahttps://plasmogem.sanger.ac.uk/base is maintained by Dr. Chris J. Janse